In my ongoing series of characters from Transformers Prime re-imagined as faculty for a High school (and stuff I draw during my train ride to and from work), I had to think for a bit as to where all to put 'Screamer.
It was suggested that he would be a Vice Principal and that makes sense in the usual continuities... but I didn't want to fall into that troupe given that the "main characters" wouldn't be the teachers and staff but the students. I thought about making him the school secretary and handler of the morning announcements but that doesn't quite work either.
Then it came to me that Starscream would be the kinda weird eccentric teacher that's always trying to be cool with the students and is a bit over the top. He's the type that would read Shakespeare in an accent or come into class dressed in period garb. Thus he would be best suited to being the Cybertronian Literature Teacher! I think he'd also manage the Drama Club